PATIENTS & CAREGIVERS
Gelclair® - Bioadherent oral protective gel for mucositis relief

 

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What is Oral Mucositis?

Oral mucositis is an acute inflammation and ulceration of the surface of the mouth and throat. Oral mucositis is a significant problem in patients receiving chemotherapy or radiotherapy. It is a painful condition that can limit adequate nutritional intake.

 

 

 

 

 

What is the Incidence of Oral Mucositis?

  • 100 % of patients receiving Head & Neck radiotherapy1,2
  • up to 100% of patients undergoing high-dose chemotherapy with hematopoietic stem cell transplantation3,4
  • 30-75% of patients receiving chemotherapy1

 

What is the effect of Oral Mucositis on patients' daily life?

The patients could feel pain and troubles in5-7

  • Eating and drinking 
  • Speaking 
  • Swallowing 
  • Sleeping 

What is Gelclair®?

Gelclair® is a viscous oral gel for the management of oral mucositis due to radiation/chemotherapy.
Gelclair® exerts a mechanical action that provides rapid pain relief by adhering to the mucosal surface of the mouth, and by preventing over stimulation of exposed and sensitized verve ending within the mucosa.

 

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How does Gelclair® work?

When Gelclair® is rinsed around the mouth, PVP and sodium hyaluronate create a barrier over the oral mucosa.

This barrier can reduce pain and enable patients to eat and drink more easily, as it shields the nerve endings underneath. 

MOA1.png Without Gelclair®

MOA2.png With Gelclair®

 

How to use Gelclair®?

 

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For more information, please contact the local distributor of your country.

 

References
1. Epstein, Schubert. Oncology 2003; 17: 1767-82.
2. Peterson et al. Ann Oncol 2009; 20 (suppl 4): 174-7.
3. Sonis. J Support Oncol 2004; 2 (6 suppl 3): 3-8.
4. Silverman. J Support Oncol 2007; 2 (2 suppl 1): 13-21.
5. Sonis et al, J Clin Oncol. 2001; 19: 2201-2205.
6. Bellm et al, Support Care Cancer 2000; 8: 33-39.
7. Bruce and Quinn, US Oncological Disease 2007; 86-90.

 

 

 

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