Treatment-related risk factors are directly linked to radio- and chemotherapy regimens:
- CT and RT directly assault the oral mucosa.
- Many CTs are known to cause oral mucositis even at standard doses.
- Risk level depends on the antineoplastic therapy, as well as on the dose and treatment schedule.
Risk increases in case of combined radio-chemotherapy.
Cawley. Clin J Oncol Nurs 2005; 9(5).
Sonis. J Support Oncol 2004; 2(Suppl 3):3-8.